Avastin in combination with pemetrexed delivers promising outcomes
Phase II trial (Waples, et al.): Avastin in combination with pemetrexed/oxaliplatin first line followed by Avastin maintenance
Phase II trial16
- Patients received six cycles of first-line Avastin 15mg/kg in combination with pemetrexed 500mg/m2 and oxaliplatin 120mg/m2, with Avastin 15mg/kg then continued as monotherapy until PD (maintenance).16
- Interim efficacy data following first-line therapy16
- median PFS: 7.8 months
- median OS: 16.7 months.
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