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Professor Jean-Charles Soria reviews efficacy and safety data for Avastin plus chemotherapy across clinical trials in NSCLC at the Roche Anti-angiogenesis Investigator Meeting during ASCO 2010 in Chicago, USA in June 2010.

SAiL investigator Professor Lucio Crino discusses the clinical relevance of newly reported data for Avastin in NSCLC.

Professor Roman Pérez-Soler summarises the current state of knowledge and evolving concepts regarding malignant transformation and cancer pathogenesis.

Dr Anne Tsao highlights the efficacy of first-line Avastin in combination with chemotherapy in non-squamous NSCLC at the Horizons IV Lung Cancer Expert Forum in Berlin, Germany in September 2009.

Professor Fairooz Kabbinavar discusses angiogenesis – a fundamental process for tumour growth – and how Avastin targets VEGF, the key driver of angiogenesis, at the Anti-angiogenesis Clinical Experience Exchange Meeting in Madrid, Spain in April 2009.

Professor Camillo Porta presents the latest clinical trial data on the efficacy of first-line Avastin plus IFN in mRCC at the F. Hoffmann-La Roche satellite symposium at ECCO/ESMO 2009 in Berlin, Germany in September 2009.

Professor Frank Griesinger presents the latest clinical trial data on the efficacy of first-line Avastin-based therapy in advanced NSCLC at the F. Hoffmann-La Roche satellite symposium at ECCO/ESMO 2009 in Berlin, Germany in September 2009.

This slide deck summarises the data on the anti-angiogenic effects of Avastin, including regression of tumour vasculature, normalisation of surviving vasculature and inhibition of new and recurrent tumour vessel growth.
This slide deck presents findings from a retrospective analysis of more than 12,000 patients across several tumour types, which demonstrated that the risk of cerebral haemorrhage, in the presence of CNS metastases, is independent of Avastin therapy.
This presentation highlights some of the known prognostic and predictive angiogenesis biomarkers used in oncology. Through clinical trials of Avastin, a number of potential biomarkers have been identified.