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SAiL: low incidence of AEs of special interest

SAiL: low incidence of severe AEs in the SAiL trial


 
SAiL: incidence of AEs (all grades and grade 3-5)

SAiL: incidence of AEs of special interest (all grades and grade 3–5)12

Reprinted with the kind permission of the author.

SAiL: incidence of AEs by outcome and action taken

SAiL: incidence of AEs of special interest by outcome and action taken12

Reprinted with the kind permission of the author.


  • The majority of AEs of special interest related to Avastin were grade ≤2.
  • The rates of grade ≥3 hypertension, haemoptysis and GI perforation were low.
  • The incidence of grade ≥3 pulmonary haemorrhage/haemoptysis was low (0.7%).
  • No cases of CNS haemorrhage have been reported in patients previously diagnosed with CNS metastases.
 

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