SAiL: low incidence of AEs of special interest
SAiL: low incidence of severe AEs in the SAiL trial
- The majority of AEs of special interest related to Avastin were grade ≤2.
- The rates of grade ≥3 hypertension, haemoptysis and GI perforation were low.
- The incidence of grade ≥3 pulmonary haemorrhage/haemoptysis was low (0.7%).
- No cases of CNS haemorrhage have been reported in patients previously diagnosed with CNS metastases.
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