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ECOG 4599: first-line Avastin-based therapy – the first combination to achieve OS beyond the historical benchmark of 1 year

Avastin-based therapy extends survival beyond conventional paclitaxel/carboplatin chemotherapy, with OS >1 year


 
ECOG 4599: OS

ECOG 4599: OS5

Copyright ©2006 Massachusetts Medical Society. All rights reserved.


  • In ECOG 4599, the addition of a platinum doublet to Avastin significantly increased OS, PFS and ORR in the overall non-squamous NSCLC population versus chemotherapy alone.5
  • Median OS increased from 10.3 to 12.3 months with Avastin-based therapy (HR=0.79).5
 

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