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Combining Avastin with conventional chemotherapy leads to superior efficacy

  • The specific chemotherapy agents used in clinical practice vary considerably between tumour types; trials have investigated Avastin in combination with the most frequently used regimens in each indication.
 
  • Avastin has demonstrated efficacy in phase III trials when combined with a variety of chemotherapy agents and regimens
    • mCRC: IFL, XELOX, FOLFOX47,28
    • NSCLC: carboplatin/paclitaxel, cisplatin/gemcitabine8,12
    • mBC: paclitaxel, docetaxel.9,14
 
  • Large safety studies have explored further combinations in mCRC, NSCLC and mBC.29–32
Chemotherapy agents
 

Chemotherapy agents and regimens used in combination with Avastin in safety studies29–32