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Efficacy in combination with a broad range of standard therapies

  • Combining anticancer agents with different MoA may lead to increased efficacy through additive, and even synergistic, effects

    • the precise nature of VEGF inhibition by Avastin makes this agent an ideal partner for combination with approaches aimed at other mechanisms of tumour proliferation.24,25

  • Additional benefit may be gained through normalisation of tumour vasculature by Avastin, which reduces interstitial pressure and increases the delivery of other agents to the tumour. 26,27

  • This section provides an overview of the clinical efficacy of Avastin in combination with different types of anticancer agent.

 

Avastin demonstrates efficacy in combination with conventional chemotherapy
Avastin in combination with other standard anticancer agents and treatment modalities